Safety of using genetic engineering biological agents in rheumatoid arthritis
نویسندگان
چکیده
منابع مشابه
Biological agents in rheumatoid arthritis.
Rheumatoid arthritis (RA) is the commonest inflammatory joint disease with considerable morbidity and mortality. Conventional disease-modifying antirheumatic drugs like methotrexate form the cornerstone of therapy. However, they have several limitations in terms of slow onset of action, adverse effects and modest remission and retention rates. Several cytokines are involved in the pathogenesis ...
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A wealth of studies has demonstrated that patients with rheumatoid arthritis (RA) are at increased risk of cardiovascu-lar morbidity and mortality, and that this increase is manifest early in the course of RA. 1 2 Another wealth of studies has shown the increasing effi cacy of recent therapies, or therapeutic strategies, in reducing disease activity in RA. As the infl ammatory burden in RA may ...
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While initial researches documented that Rheumatoid Arthritis (RA) patients who took biologic agents had decreased symptoms with those receiving traditional treatment, safety of the drugs remains a concern. The authors in this paper review the safety of the RA new therapeutic approach utilizing biological agents and compare it with the safety of conventional disease-modifying anti-rheumatic dru...
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بیماری روماتیسم قلبی یکی از شایعترین علل مرگ و میر ناشی از بیماریهای قلبی و عروقی در کشورهای در حال توسعه می باشد. براساس بررسیهای انجام شده، میزان شیوع بیماری در جامعه و مدارس از ۱ الی ۲۲ در هر هزار نفر کودک می باشد. تخمین زده میشود که تعداد مبتلایان به بیماریهای مزمن روماتیسم قلبی در کشورهای در حال توسعه ۳۰ میلیون و در کشورهای صنعتی ۱ / ۵ میلیون باشد. بسیاری از موارد مرگ و میر ناشی از این بیم...
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ژورنال
عنوان ژورنال: Modern Rheumatology Journal
سال: 2010
ISSN: 2310-158X,1996-7012
DOI: 10.14412/1996-7012-2010-587